Sonic hedgehog maintains the identity of cortical interneuron progenitors in the ventral telencephalon. Fate determination in the mammalian forebrain, where mature phenotypes are often not achieved until postnatal stages of development, has been an elusive topic of study despite its relevance to neuropsychiatric disease. In the ventral telencephalon, major subgroups of cerebral cortical interneurons originate […]
Tag Archives: MGE
15
Jan
Vitamin Named after Sonic The Hedgehog
Posted by Dhawal D |
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Tagged cell, cell fate, co express, composition, contrast, cortex, Cre, determination, Dlx, dramatic reduction, elusive topic, eminence, expression, feeder, gene, index, interneurons, mammalian forebrain, medial, MGE, mutant mice, mutants, NestinCre, neural, neural tube, neuropsychiatric disease, parvalbumin, period, progenitors, reduction, somatostatin, sonic hedgehog, sonic the hedgehog, stages of development, study, topic, ventral, vitro